ADHD Medications - What Are the Side Effects?
Many people suffering from ADHD are prescribed medication. It can improve symptoms but it can also trigger negative side effects. Speak to your doctor in the event of any adverse reactions.
The most common prescription medication prescribed by healthcare providers for ADHD is stimulants. These medications increase the levels of brain chemicals known as neurotransmitters, which control the attention span and behavior.
Methylphenidate

Methylphenidate is a stimulant of first choice used to treat ADHD in children and adults. It works by increasing the activity of brain regions that control attention and behavior. Methylphenidate is also used to treat other conditions such as narcolepsy. It can aid people suffering from narcolepsy to stay awake and improve their ability to focus and pay attention.
This medication has a high risk of abuse and is classified as a Schedule II drug in the US Drug Enforcement Agency. If you take this medication as prescribed will reduce the risk for abuse and also other side effects. Methylphenidate may trigger psychotic symptoms in some people. It can also increase the severity of behavior and tics for some people with Tourette syndrome or bipolar disorder. Patients with these conditions should tell their doctor before starting this medication.
It is important to inform your doctor if there are any other health problems or are sensitive to any food or dyes (such as tartrazine, a yellow color present in processed foods and in some medications or if you're taking Adhansia XR). Methylphenidate may interact with certain medications, including opioids such as antidepressants, antidepressants, and monoamine oxidase inhibitors like isocarboxazid (Marplan) and linezolid (Zyvox) Methylene blue, phenelzine (Nardil), rasagiline (Azilect) selegiline (Eldepryl, Emsam, Zelapar) or tranylcypromine (Parnate).
It's also important to avoid alcohol and other stimulant substances when taking methylphenidate. These medications can have a negative impact on your heart rate and blood pressure. The methylphenidate tablets that are immediate-release (Ritalin) as well as the oral disintegrating capsule with a long-acting mechanism and chewable tablets (Quillichew-ER and Cotempla XR-ODT), and the long acting chewable tablets (Quillichew-ER and Cotempla-XR-ODT), contain Phenylalanine. It can be a risk if a genetic condition known as phenylketonuria exists.
Bupropion
Bupropion is an antidepressant medicine that works within the brain to improve mood and reduce symptoms of ADHD. It is also used for depression and seasonal depression (SAD), which occurs during the fall-winter months. It can also help smokers quit by reducing the craving for nicotine and withdrawal symptoms.
Bupropion has been shown to improve ADHD symptoms in adults in a variety of studies. The pooled fixed effect RR for improvements in week 6 (using an increase in clinical significance of 30% or greater on the CGI) is 1.14 (95%CI 0.95-1.37). For overall response, this equates to 52 percent of the bupropion group and 37% in the placebo group.
Bupropion could cause serious and sometimes life-threatening interactions various drugs, including sedatives antidepressants, and some blood pressure medications. It can also increase the risk of seizures in people with a history of seizure or high blood pressure. It is also not recommended for people suffering from certain medical conditions and is not recommended for women who are nursing or pregnant. Bupropion is available in the form of brand-name drugs Wellbutrin SR and Wellbutrin XL. It is also available in the form of Zyban, Budeprion SR. Aplenzin and Forfivo XL. It is also available in generic form.
Tricyclic antidepressants
Tricyclic antidepressants (abbreviated TCAs) are a class of drugs that alter brain chemicals. They were among the first antidepressants developed. While they aren't used as a first line treatment for depression anymore but they can be effective for certain people. They work by blocking the reuptake of dopamine and serotonin, increasing their levels of availability in neurons. They can be used to treat a variety of other conditions, including enuresis, pain syndromes such as fibromyalgia, and phantom-limb syndrome.
TCAs are effective for ADHD symptoms, whether they are prescribed on their own or in combination with stimulants. They can alleviate symptoms that are core to the disorder, and can reduce depression, anxiety and impulsiveness. In addition, they could help manage tics, which are repetitive uncontrollable movements or sounds like clearing the throat or blinking.
TCAs can cause adverse effects, such as dry mouth and sedation and may increase the risk of heart problems. These medications can interfere with other medications, such as anticholinergics and should not be used by women who are pregnant. They can also be teratogenic for animals and can cross the placenta. Talk to your doctor if concerned. There are antidepressants that are more recent that have a lower risk of adverse effects.
Selective serotonin Reuptake inhibitors (SSRIs)
The SSRIs are antidepressants. They consist of a class of drugs that block serotonin reuptake in neurons and aid in increasing the amount of serotonin available to signal. They also decrease anxiety and decrease impulsive behavior. They are often used as adhd medication since they can improve symptoms in certain people and can be helpful in conjunction with other medications. SSRIs include fluoxetine, sertraline paroxetine, and citalopram. They have linear pharmacokinetics and have low clearance from the body, however they are extensively metabolized the liver by CYP450 isoenzymes. This results in varying blood concentrations.
These drugs can also be prescribed to treat other disorders such as posttraumatic stress disorder (PTSD) as well as generalized anxiety disorder and the bulimia-nervosa. The SSRIs fluoxetine, escitalopram, and sertraline may help to reduce PTSD core symptoms. They aren't effective in treating other PTSD symptoms.
SSRIs may cause a very rare side effect known as sexual dysfunction. If you are thinking about taking one of these drugs it is essential to talk with your doctor. A lot of people must try a few different types of ADHD medication before they find the one that works for them. There are always new medications being developed and studied. It is important to inform all medications you take to your physician.
Selective norepinephrine reuptake inhibitors (SNRIs).
When stimulant drugs do not help adults suffering from ADHD doctors recommend an inhibitor of selective norepinephrine reuptake (SNRI). These drugs increase levels of norepinephrine as well as serotonin, two brain chemicals. They also improve mood and reduce depression and anxiety.
SNRIs are similar to TCAs however they are safer and have fewer side effects. They are used for many ailments like anxiety disorders, chronic pain such as fibromyalgia and nerve pain. They can also be employed as an adjunct treatment for depression. SNRIs are duloxetine, (Cymbalta) and venlafaxine (Effexor).
These drugs block the reabsorption of norepinephrine into the brain which is a normal process after neurotransmission. medications for adhd causes a greater than normal release of phasic. The increased norepinephrine levels help increase concentration and mood.
Although SNRIs aren't approved by the FDA to treat ADHD, some doctors use them as a substitute for stimulants. They are most often taken orally in the form of pills, but they can be taken as liquids or patches. In April 2021, the FDA approved an oral SNRI known as viloxazine (Qelbree) to treat ADHD in adolescents and children. It is not a controlled medication since it doesn't have the potential to be misused.
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
SNRIs are antidepressants that affect the levels of serotonin and norepinephrine within the brain. They are used to treat anxiety and depression disorders, but can aid in the treatment of symptoms of ADHD. SNRI drugs like duloxetine or venlafaxine have been proven in numerous studies to significantly decrease scores on a variety of ADHD questionnaires. However, SNRIs can increase a person's blood pressure and may interact with certain medications. It is crucial to consult with a physician prior taking these medications. In addition, improperly disposed medication could cause harm to people and animals. Therefore, it is essential to follow the proper disposal guidelines.
SSRIs or SNRIs haven't been approved by the FDA to treat ADHD however, doctors can prescribe them off-label. They are safe, effective, and have less adverse effects than stimulants. Talk to your doctor and discuss your child's health concerns.
SNRIs can raise the levels of serotonin and norepinephrine, however, they are not appropriate for everyone. For example women who are pregnant or breastfeeding should not take SNRIs as they could be passed into breast milk. They should not be taken by those who suffer from high blood pressure, liver problems or any other cardiovascular problems.
Selective dopamine Reuptake inhibitors (DARPIs)
Many people with ADHD find that medication helps improve their attention and focus. They might also experience less impulsive behaviors. The treatment is usually paired with behavioral therapy and training, which help people learn to control their symptoms. Finding the right medication for each person takes time. During this time, doctors will monitor the physical reactions of patients to find a balance between the effects of side effects and the benefits.
Stimulant drugs, such as methylphenidate, boost the activity of certain brain chemicals that regulate memory and attention. Although they are generally safe and effective for most people, they can trigger serious side effects like decreased appetite and difficulty sleeping. These side effects usually subside after a couple of days as your body adjusts to the medication.
Adults and children alike can use non-stimulant drugs. They may take longer to effect their effects however they can help improve impulse control and concentration. They could include alpha-2 adrenergic antagonists (atomoxetine viloxazine, atomoxetine) and guanfacine hydrochloride.
Antidepressants are also effective in treating ADHD. They can boost norepinephrine levels which is a neurotransmitter found in the brain that assists with mood swings and depression. Bupropion, an antidepressant, has been prescribed to treat ADHD. It was prescribed "off-label", but drugmakers developed extended-release versions, and the FDA approved the use of it as a treatment.